Patient Information
Mission
nQ’s mission is to improve lives, by enabling the discovery and development of digital biomarkers. We are grateful to the patients, healthy volunteers, families, hospitals and clinics that have chosen to participate in our previous and ongoing clinical studies.
Participation in clinical research contributes valuable information that allows our scientists to better understand the safety and effectiveness of our digital biomarkers.
Before a new biomarker can be made available to the general public, multiple studies involving healthy volunteers and patient volunteers must be conducted. Each individual’s participation contributes enormously to our understanding of disease and has the potential to benefit patients around the world.

nQ is conducting numerous clinical studies in neurologic diseases to evaluate the efficacy and safety of potential digital biomarkers.
- View our current pipeline to learn more about clinical studies for specific conditions
- See detailed information on currently enrolling clinical trials for nQ investigational and digital biomarkers on clinicaltrials.gov
- Learn more about our clinical studies, why they are important, what they involve, and view our currently enrolling U.S. trials for:
Parkinson’s Disease
The effective treatment of PD is based on lifestyle and pharmacologic interventions that improve quality of life. Today, adjustments to medication regimens for Parkinson’s Disease (PD) patients are limited to information gathered by movement disorder specialists during on-site clinical examinations approximately every 6 months.
Current clinician assessment tools help provide objectivity and standardization to the clinical exam, however, due to the inherently subjective nature of physician-patient interview and the large degree of fluctuation in PD symptoms high degrees of inter-rater and intra-rater variability are still observed even when administered by highly trained professionals.
Additionally, these scales are not optimized to detect subtle motor fluctuations that can be present in early disease.

nQ is changing how patients, families, doctors and scientists think about brain disease. Now we need you. Whether you have PD or not, you can make a difference.
Alzheimer’s Disease

There is an urgent need to identify individuals manifesting initial symptoms of AD for the purpose of testing of new agents in clinical trials, to facilitate lifestyle modifications that impact disease course.
In the event that disease modifying therapies become mainstream, early identification of cognitive impairments combined with treatment will become crucial to maintain quality of life and improve outcomes.
Although several diagnostic tests are available that can identify patients in the earliest stages of the disease, these tests are prohibitively expensive (amyloid PET) or invasive (spinal tap) and are not feasible for screening millions of at-risk individuals.
New screening tools that are inexpensive, scalable, and minimally invasive are urgently needed to combat the looming Alzheimer’s disease epidemic.
nQ is changing how patients, families, doctors and scientists think about brain disease. Now we need you. Whether you have AD or not, you can make a difference.
Amyotrophic Lateral Sclerosis (ALS)
Current methods to evaluate and monitor symptom severity in people with ALS rely on questionnaires, which are subjective and are designed to be done with the patient in clinic.
Perhaps the most commonly used outcome measure is the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R), a 12-item questionnaire aimed at monitoring the progression of disability across four domains: gross motor tasks, fine motor tasks, bulbar function and breathing function.
By its nature, ALS is a heterogeneous disorder that can primarily affect any of these domains. Yet by using a scale that covers such a broad array of symptoms, we lose the ability to perform detailed tracking of disease progression in any one of these domains.

nQ is changing how patients, families, doctors and scientists think about brain disease. Now we need you. Whether you have ALS or not, you can make a difference.
Multiple Sclerosis (MS)

Gold standard outcome measures for clinical trials in MS have historically included annualized relapse rate and the Expanded Disability Status Scale (EDSS), a relatively insensitive measure of disease progression.
While these and other clinical outcome measures such as those included in the MS Functional Composite are familiar to and interpretable by clinicians and clinical researchers, they fail to assess many domains that are significant to PwMS.
Patient reported outcome (PRO) data that capture additional important dimensions of the MS experience are therefore increasingly being recognized as valuable tools for evaluating disease symptoms, quality of life, the effectiveness of therapies, and the status of disease progression in PwMS, both in clinical trials and in routine clinical evaluations.
nQ Medical (nQ) proposes that passive tools that collect data continuously in the remote environment have the potential to provide digital biomarkers as SAMD that track closely with PRO data across a number of functional domains to provide a solution that addresses unmet medical needs while advancing modern care and drug development.
nQ is changing how patients, families, doctors and scientists think about brain disease. Now we need you. Whether you have MS or not, you can make a difference.